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Biocatalysis Chemist


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Title: Biocatalysis Chemist
Time Period:18 Months
Location: Groton, CT

Job Role:
The biocatalysis chemist will work with the team to develop and operationalize standard biocatalysis screening process (platforms) to support the Integrated Oxidative Platform (IOP) for lead diversification of medicinal chemistry compounds. A background in organic/analytical chemistry along with using automated liquid handlers is required.

Primary Duties:
Responsible partnering with teams to ensure timely delivery of project objectives.
In collaboration with scientists, operationalize and integrate various screening platforms/technologies into the IOP workflow.
Leverages scientific expertise in analytical chemistry to identify screening hits with optimum product yield so that optimal conditions and parameters can be deduced to produce desired material on scale (multi-milligrams grams).
Write SOPs for operationalized process and effectively communicate results to teams.

Training, Education and Primary Experience Preferred:

Bachelors / Masters level degree or equivalent with at least 2-4 years of experience in the pharmaceutical industry.
Strong working knowledge of biocatalysis and analytical chemistry with organic chemistry and Tecan liquid handler knowledge.
Demonstrated track record of technical problem solving in areas of biocatalysis, analytical chemistry and organic chemistry.
Experience with automated platforms.
Track record of solid teamwork and collaboration.
Proficient with modern computer software and Microsoft Office package.

Top three critical skills: Biocatalysis and/or organic chemistry experience. Experience with automated platforms. Analytical chemistry experience.

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